

True to its name, ulcerative colitis involves the chronic formation of ulcers within the colon, or bowel. (The limitation of symptoms to this part of the large intestine sets it apart from Chron's disease, in which inflammation may occur throughout the digestive tract.) The ulceration is triggered by the body's own defense mechanism, the immune system. This system normally wards off invading viruses and bacteria, but in people with ulcerative colitis it also mistakenly attacks food particles or non-harmful intestinal microorganisms. The resulting inflammation accompanies the development of sores that emit mucous and pus. Patients typically suffer from diarrhea, rectal pain, chronic abdominal cramps, and frequent, often bloody stools. They may also feel the need to make frequent trips to the restroom. Severe blood loss from long-term bouts of ulcerative colitis may put some individuals at risk for anemia, or low red blood cell count. Other possible complications include osteoporosis, dehydration, liver problems, a perforated colon, and a heightened risk for colon cancer.

Treatment of ulcerative colitis is aimed at reducing the severity of the symptoms, there is presently no known cure for the condition. Anti-inflammatory and immune-suppressant drugs are commonly prescribed to control the condition. Physicians may also prescribe lifestyle adjustments and remedies such as smaller meals, vitamin supplements, and avoidance of certain foods such as dairy items and high-fiber products.
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